
Sarah Maria Stiegeler
About
Independent, highly motivated and enthusiastic researcher with six years of experience in Industrial R&D and a PhD thesis submitted in Microbiology.
Social Media:
Skills
ADMET
Animal Breeding
Barrier
Functional Analysis
Host-pathogen Interactions
Independent Thinking
Industrial Microbiology
Infection
Microbiology
Molecular Biology
Molecular Microbiology
Mucosal Immunology
MiRNA
NMR Spectroscopy
Onboarding
Pharmaceutical Microbiology
QRT-PCR
RNAseq
Scientific Analysis
Scientific Data Management
Scientific Writing
Soft Skills
Student Supervision
Tissue Culture
Translational Research
Western Blotting
Open for
fulltime
cofounder
Work Experience
Polyphor Ltd
2014-10 - 2020-12
Scientist Microbiology
Basel-Landschaft
fulltime
Contributed to the discovery and preclinical development of novel antimicrobial compounds, including LptA Thanatin derivatives, OMPTA (LPS/BamA), and LptD/E (Murepavadin), covering early discovery to preclinical profiling. Conducted ADMET characterisation alongside extensive antimicrobial susceptibility testing (MIC, MBC, kill kinetics, resistance liability) using MDR/XDR strains. Performed mode-of-action studies and optimised established high-throughput workflows, enhancing assay efficiency and implementing robust QC checkpoints. Co-inventor of Antimicrobial Peptidomimetics, with significant contributions to assay development strategies addressing resistance emergence. Supported clinical-stage activities through evaluation of patient recruitment strategies. Managed BSL-2 laboratory operations, including facility oversight, procurement, inventory, and compliance. Collaborated across multidisciplinary teams and contributed to training and knowledge transfer within the organisation.
Academic Experience
Trinity College Dublin -
2021.02 - 2024.01
Philosophical Doctorate, PhD in Microbiology
University College Cork -
2024.01 - 2026.04
Philosophical Doctorate, PhD in Microbiology