

Selena Di Maio
Location
Zürich
Field of Study
Chemistry / Chemical Engineering
Expertise
Management, Preclinical R&D, Digital Health
About
R&D Scientist
I work at the interface of research and drug development to develop strategies to identify and execute pharmacometric support to key decisions in preclinical modeling, early clinical development and translational medicine. I manage external collaborations and outsourced preclinical in vivo studies for the intere DMPK and PK/PD department. My current focus is on oncology and anti-infectives. I have experience in developing small molecules and peptides as well.
Social Media:
Skills
ADMET
Bioanalysis
Biological Data Analysis
CRO Management
Collaborative Leadership
Collaborative Project Management
DMPK
Drug Delivery
Drug Development
Modeling and Simulation
Operations Management
PK/PD
Pre-clinical Studies
Rheology
Solid Oral Dosage Forms
Open for
cofounder
fulltime
Work Experience
Polyphor AG
2019-11 -
DMPK Scientist PK/PD modeling
Basel-Landschaft
fulltime
• Pharmacokinetics/Pharmacodynamics – plan, review and analyze preclinical PK, TK and PK/PD studies to support the design and selection of new drug candidates. • Model-based drug development – plan and execute PK/PD modeling and simulation analysis to support pre/clinical, safety and translational strategies for peptides. • In vivo study management responsibilities – coordinate external laboratory activities in pharmacology, metabolism, PK and TK studies.
Topadur Pharma AG
2018-09 - 2019-09
Research Investigator Pre-Clinical Drug Development
Zürich
fulltime
• Pharmacokinetics/Toxicokinetics – plan, review and analyze preclinical PK and TK studies to support the design and selection of new drug candidates. • Analytical and bioanalytical methods development and validation – plan, develop and execute HPLC-MS/MS based analysis of new drug entities in biological matrices. • Project management responsibilities – coordinate laboratory activities in order to meet challenging deadlines
UCSF - University of California San Francisco
2014-06 - 2016-12
Postdoctoral Scholar
San Francisco - California USA
fulltime
• My research projects focused on innovative in vitro – in vivo approaches aimed to the discovery of novel biomarkers for asthma and to the development of rheologybased drug screening tools for cystic fibrosis (published one peer-reviewed paper). • Biopolymer engineering - Developed and characterized novel thiol-modified hydrogels as screening tool for novel drug entities. • Rheology methods development for human specimen and hydrogels characterization. • Advanced cellular biology assays development with primary human cells for use in drug cytotoxicity testing, immunology assays, and gene expression analysis.
Academic Experience
Northeastern University - Boston, MA (USA) -
2009.01 - 2014.04
Philosophical Doctorate, PhD in Chemical engineering
Università di Bologna (Italy) -
2004.09 - 2007.07
Master of Science, MSc in Chemistry