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Selena  Di Maio

About

R&D Scientist

I work at the interface of research and drug development to develop strategies to identify and execute pharmacometric support to key decisions in preclinical modeling, early clinical development and translational medicine. I manage external collaborations and outsourced preclinical in vivo studies for the intere DMPK and PK/PD department. My current focus is on oncology and anti-infectives. I have experience in developing small molecules and peptides as well.

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Skills

ADMET

Bioanalysis

Biological Data Analysis

CRO Management

Collaborative Leadership

Collaborative Project Management

DMPK

Drug Delivery

Drug Development

Modeling and Simulation

Operations Management

PK/PD

Pre-clinical Studies

Rheology

Solid Oral Dosage Forms

Open for

cofounder

fulltime

Work Experience

Polyphor AG

2019-11 -

Workplace
DMPK Scientist PK/PD modeling
Location

Basel-Landschaft

Employement type

fulltime

• Pharmacokinetics/Pharmacodynamics – plan, review and analyze preclinical PK, TK and PK/PD studies to support the design and selection of new drug candidates. • Model-based drug development – plan and execute PK/PD modeling and simulation analysis to support pre/clinical, safety and translational strategies for peptides. • In vivo study management responsibilities – coordinate external laboratory activities in pharmacology, metabolism, PK and TK studies.

Topadur Pharma AG

2018-09 - 2019-09

Workplace
Research Investigator Pre-Clinical Drug Development
Location

Zürich

Employement type

fulltime

• Pharmacokinetics/Toxicokinetics – plan, review and analyze preclinical PK and TK studies to support the design and selection of new drug candidates. • Analytical and bioanalytical methods development and validation – plan, develop and execute HPLC-MS/MS based analysis of new drug entities in biological matrices. • Project management responsibilities – coordinate laboratory activities in order to meet challenging deadlines

UCSF - University of California San Francisco

2014-06 - 2016-12

Workplace
Postdoctoral Scholar
Location

San Francisco - California USA

Employement type

fulltime

• My research projects focused on innovative in vitro – in vivo approaches aimed to the discovery of novel biomarkers for asthma and to the development of rheologybased drug screening tools for cystic fibrosis (published one peer-reviewed paper). • Biopolymer engineering - Developed and characterized novel thiol-modified hydrogels as screening tool for novel drug entities. • Rheology methods development for human specimen and hydrogels characterization. • Advanced cellular biology assays development with primary human cells for use in drug cytotoxicity testing, immunology assays, and gene expression analysis.

Academic Experience

Northeastern University - Boston, MA (USA) -

 

2009.01 - 2014.04

Philosophical Doctorate, PhD in Chemical engineering

Università di Bologna (Italy) -

 

2004.09 - 2007.07

Master of Science, MSc in Chemistry